Japanese researchers have found that all variants of SARS-CoV-2, the virus that causes Covid, were in fact made in a laboratory.
The study, led by Japanese professors Atsuki Tanaka and Takayuki Miyazawa of Osaka Medical University and Kyoto University, sought to trace the historical evolution of the omicron variant of the virus.
To trace the variant’s origins, Tanaka and Miyazawa wrote in a new paper titled “Unnaturalness in the Evolution Process of the SARS-CoV-2 variants and the possibility of deliberate natural selection”, they studied viral sequences found “in the wild” and deposited in public databases.
The researchers said they found around 100 separate omicron subvariants that could not conceivably have arisen through natural processes.
The existence of these variants seems to provide definitive proof of large-scale lab creation of Covid viruses, Tanaka and Miyazawa wrote.
Tanaka and Miyazawa state in the paper:
"Over the past three years, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has repeatedly caused pandemics, generating various mutated variants ranging from Alpha to Omicron. In this study, we aimed to clarify the evolutionary processes leading to the formation of SARS-CoV-2 Omicron variants, focusing on Omicron variants with many amino acid mutations in the spike protein among SARS-CoV-2 isolates.
"To determine the order of mutations leading to the formation of the SARS-CoV-2 Omicron variants, we compared the sequences of 129 Omicron BA.1-related, 141 BA.1.1-related, and 122 BA.2-related isolates, and attempted to clarify the evolutionary processes of SARS-CoV-2 Omicron variants, including the order of mutations leading to their formation and the occurrence of homologous recombination.
"As a result, we concluded that the formation of a part of Omicron isolates BA.1, BA.1.1, and BA.2 was not the product of genome evolution, as is commonly observed in nature, such as the accumulation of mutations and homologous recombinations. Furthermore, the study of 35 recombinant isolates of Omicron variants BA.1 and BA.2 confirmed that Omicron variants were already present in 2020.
"The analysis showed that Omicron variants were formed by an entirely new mechanism that cannot be explained by previous biology, and knowing how the SARS-CoV-2 variants were formed prompts a reconsideration of the SARS-CoV-2 pandemic."
The researchers continue: "In the genetic variation in the S protein in these variants, most of the mutations were non-synonymous. There were no synonymous mutations in the Alpha, Beta, Gamma, Delta, or Mu variants, but only one each in the Lambda and Omicron variants. Among these variants, the Omicron variant (BA.1 lineage), which shows the greatest accumulation of mutations in the S protein, is primarily non-synonymous in the S protein and has only one synonymous mutation at c25000u. The synonymous/non-synonymous ratio is abnormal, given how human coronaviruses have mutated."
In an analysis of the research, Slay News notes: "In this context, 'synonymous' normally refers to something that mutates naturally. A 'synonymous' mutation does so mostly in ways that don’t change the nature of the original. Therefore, when you have a 'synonymous/non-synonymous ratio' that is as 'abnormal' as that of the Covid variants, that means they are not occurring naturally."
Tanaka and Miyazawa said they could not conclude "that these viruses were artificially synthesized and distributed based on malicious intent."
But they did assert that the variants could not have formed naturally, meaning they could have only been engineered in a lab.
“The analysis we have shown here concludes that the Omicron variants are formed by a completely new mechanism that cannot be explained by previous biology,” they conclude.
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